What are the symptoms of multiple myeloma?

Signs and symptoms of myeloma include:

  • Bone pain, often in the back
  • Bone fractures
  • Frequent infections, particularly pneumonia
  • Fatigue
  • Unexplained weight loss
  • Confusion
  • Fluid buildup in the legs
  • Itching
  • Dizziness
  • Weakness and numbness in the hands or feet

In some cases, myeloma does not cause symptoms – called smoldering myeloma – and is diagnosed unexpectedly during a blood test for another reason. Smoldering myeloma is monitored but not treated until it causes symptoms.

How is multiple myeloma diagnosed?

Your diagnosis will begin with an assessment of your symptoms and a physical exam. If your doctor suspects myeloma, he or she will order diagnostic tests to confirm the condition and stage its progression.

Diagnostic testing for myeloma at Miami Cancer Institute may include:

  • Blood tests. These tests look for excessive amounts of certain blood proteins and low blood counts, which are seen in people with myeloma. They are also used to stage the cancer.
  • Urine tests. These tests can also reveal excessive amounts of blood proteins common in myeloma.
  • Bone marrow aspiration or biopsy. These tests examine a sample of liquid bone marrow or solid bone marrow for the presence of excess plasma cells, which indicate myeloma. They can also provide other information about the cancer. Your doctor obtains a bone marrow sample with a special needle that is typically inserted into the hip bone. A local anesthetic is used to numb the site of the procedure.
  • Imaging tests. Positron emission tomography (PET) or MRI scans reveal the location, size and number of myeloma tumors.
FACT Accredited

FACT Accredited

Miami Cancer Institute, part of Baptist Health South Florida, is pleased to share that our Blood & Marrow Stem Cell Transplant Program is fully FACT Accredited for stem cell transplants and cellular therapies. This accreditation provides our program national recognition of a certified program to perform stem cell transplants and cellular therapies such as CAR T-cell therapies within our Institute. Additionally, this recognition allows our team to obtain full insurance coverage for these procedures from all providers. For more information on FACT Accreditation, feel free to visit the following link.

Have questions?

We're here to help answer any questions you or your family may have.

Language Preference / Preferencia de idioma

I want to see the site in English

Continue In English

Quiero ver el sitio en Español

Continuar en español