What are the types of myeloproliferative diseases?

The several types of myeloproliferative diseases are organized by whether the bone marrow makes too many white blood cells, red blood cells or platelets. In some types, too many of more than one type of blood cell are made.

The most common types of myeloproliferative diseases are:

  • Polycythemia vera. This can involve an overproduction of any type of blood cell, though it mostly affects red blood cells.
  • Primary myelofibrosis. This is caused by certain chemicals that are released when the body makes too many platelets, leading to the formation of scar tissue in the bone marrow. As scar tissue replaces normal bone marrow tissue, too few normal blood cells are made.
  • Essential thrombocythemia. This involves an overproduction of platelets.
  • Chronic neutrophilic leukemia. This involves an overproduction of white blood cells.
  • Chronic eosinophilic leukemia. This also involves an overproduction of white blood cells.

In some cases, chronic types of myeloproliferative diseases develop into acute leukemia.

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